Combination Therapy Produces Synergistic EffectsThe use of several different products allows slightly lower doses, which diminishes the risk for side effects.When benzoyl peroxide is combined with an antibiotic, the antibiotic minimizes benzoyl peroxide irritation by controlling inflammation and the benzoyl peroxide reduces the risk of antibiotic resistance by killing resistant strains of bacteria.Antibiotics can also reduce erythema in patients whose skin is irritated by the harsher topical retinoids.Adapalene, the least irritating of the topical retinoids, has anti-inflammatory effects that can be enhanced by the addition of an antibiotic.
Realize that acne is not going to be treated with one method alone. The best acne treatments are the old "one-two punch", or the "1-2-3-4-5-6 punch".
Generally, the face should be washed two times daily using a mild cleaning agent for the face. Do note that it is usually not a good idea to wash your face too many times in a day. Doing so can make the situation worse, resulting in irritation and even more breakout.
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